Pahomii articol 2021In this article, we carry out the cost-analysis of the total premature mortality and avoidable causes of death for Moldova by applying the human capital approach. The results show that the indirect costs of avoidable mortality represent slightly over 85% of total economic losses due to premature mortality in Moldova. The highest economic losses are due to injuries, cardiovascular diseases, and alcohol and drug-related deaths. For males, the leading cause is represented by injuries, whereas for females the two leading causes include cardiovascular diseases and alcohol and drug-related deaths. The results of this study can be used for a cost-benefit analysis to design economic mitigation strategies aimed at lowering the avoidable mortality in Moldova.